Chemokine C-C motif receptor 5 and C-C motif ligand 5 promote cancer cell migration under hypoxia
نویسندگان
چکیده
منابع مشابه
CCR1 (chemokine (C-C motif) receptor 1)
Note CCR1, a member of the beta chemokine receptor family, is a seven transmembrane protein similar to G protein-coupled receptors. CCR1 is the first human CC chemokine receptor to be identified at the cDNA level. It has a functional viral homolog, US28, which is a human cytomegalovirus.The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on acti...
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Review on CXCL17, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
متن کاملCXCR 3 ( chemokine ( C - X - C motif ) receptor 3 ) Makoto
Other names: CD182; CD183; CKR-L2; CMKAR3; CXC-R3; CXCR-3; GPR9; IP10; IP10-R; Mig-R; MigR HGNC (Hugo): CXCR3 Location: Xq13.1 Note: CXCR3 is a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (CXCL10), Mig (CXCL9) and I-TAC (CXCL11). IP10, Mig and I-TAC belong to the structural subfamily of CXC chemokines, in which a single amino acid residue separates the first tw...
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Chemokines and their receptors have key roles in cancer progression. The present study investigated chemokine activity in the prostate cancer bone metastasis microenvironment. Growth and migration of human prostate cancer cells were assayed in cocultures with bone stromal cells. The migration of LNCaP cells significantly increased when co-cultured with bone stromal cells isolated from prostate ...
متن کاملVascular Stem/Progenitor Cell Migration Induced by Smooth Muscle Cell‐Derived Chemokine (C‐C Motif) Ligand 2 and Chemokine (C‐X‐C motif) Ligand 1 Contributes to Neointima Formation
Recent studies have shown that Sca-1(+) (stem cell antigen-1) stem/progenitor cells within blood vessel walls may contribute to neointima formation, but the mechanism behind their recruitment has not been explored. In this work Sca-1(+) progenitor cells were cultivated from mouse vein graft tissue and found to exhibit increased migration when cocultured with smooth muscle cells (SMCs) or when t...
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ژورنال
عنوان ژورنال: Cancer Science
سال: 2012
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2012.02259.x